6-APB Succinate

Description

Technical Overview: 6-APB Succinate (1-(1-benzofuran-6-yl)propan-2-amine butanedioate) is a certified analytical reference standard belonging to the benzofuran and substituted phenethylamine classes. Structurally, it features a 2-aminopropyl side chain appended to position 6 of the benzofuran core, representing a rigidified bioisostere of 3,4-methylenedioxyamphetamine (MDA).

Physicochemical Properties:

• IUPAC Name: 1-(1-benzofuran-6-yl)propan-2-amine; butanedioic acid
• CAS Number (Free Base): 286834-85-3
• Molecular Formula: C11H13NO · C4H6O4
• Molecular Weight: 293.32 g/mol (Free Base: 175.23 g/mol)
• Physical Appearance: Off-white to pale crystalline solid
• Purity Grade: ≥98.0% (determined by HPLC/GC-MS)
• Solubility: Soluble in water, methanol (MeOH), and dimethyl sulfoxide (DMSO); sparingly soluble in non-polar organic solvents
• Melting Point: Decomposes prior to uniform melt; verified by DSC

Analytical Methodologies:

• Chromatography: Suitable for HPLC-DAD, UPLC-MS/MS, and GC-MS (underivatized or derivatized via TFAA/MSTFA)
• Spectroscopy: Verified via 1H-NMR, 13C-NMR, and high-resolution mass spectrometry (HRMS)
• Forensic Utility: Ideal for cross-reactivity profiling, matrix-matched calibration curves, and mass spectral library generation

Storage & Handling:

• Recommended Temperature: Store at -20°C in an airtight container protected from light and moisture
• Handling: Hygroscopic salt form; equilibrate to room temperature in a desiccator prior to opening
• Shelf Life: Stable for a minimum of 24 months from manufacture date when stored under recommended conditions

Notice: This reference material is synthesized and distributed exclusively for analytical chemistry, forensic identification, and in vitro laboratory investigation. Not for clinical, medicinal, veterinary, or human consumption.